BiologyNature Chemical Biology
Synthetic anaplerotic modules for the direct synthesis of complex molecules from CO₂
C. Diehl, P. D. Gerlinger, et al.
This study, conducted by Christoph Diehl, Patrick D. Gerlinger, Nicole Paczia, and Tobias J. Erb, explores innovative anaplerotic strategies that enhance a synthetic CO₂-fixation pathway. The effective design and implementation of these modules resulted in a remarkable carbon-positive synthesis of 6-deoxyerythronolide B, showcasing a leap forward in synthetic metabolic networks.
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