logo
ResearchBunny Logo
Spike residue 403 affects binding of coronavirus spikes to human ACE2

Medicine and Health

Spike residue 403 affects binding of coronavirus spikes to human ACE2

F. Zech, D. Schnierthauer, et al.

This research by Fabian Zech and colleagues reveals how a single T403R mutation in the bat sarbecovirus RaTG13's Spike protein enhances its ability to infect human cells. The findings suggest that current COVID-19 vaccines provide a layer of protection against potential zoonotic threats, highlighting the importance of amino acid interactions in cross-species virus transmission.

00:00
00:00
Playback language: English
Citation Metrics
Citations
0
Influential Citations
0
Reference Count
0

Note: The citation metrics presented here have been sourced from Semantic Scholar and OpenAlex.

Related Publications

Explore these studies to deepen your understanding of the subject.

Human antibodies to SARS-CoV-2 with a recurring YYDRXG motif retain binding and neutralization to variants of concern including Omicron
Medicine and Health

Human antibodies to SARS-CoV-2 with a recurring YYDRXG motif retain binding and neutralization to variants of concern including Omicron

H. Liu, C. I. Kaku, et al.

Broad host range of SARS-CoV-2 and the molecular basis for SARS-CoV-2 binding to cat ACE2
Medicine and Health

Broad host range of SARS-CoV-2 and the molecular basis for SARS-CoV-2 binding to cat ACE2

L. Wu, Q. Chen, et al.

Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor
Medicine and Health

Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor

J. Yang, S. J. L. Petitjean, et al.

Influence of stress induced by the first announced state of emergency due to coronavirus disease 2019 on outpatient blood pressure management in Japan
Medicine and Health

Influence of stress induced by the first announced state of emergency due to coronavirus disease 2019 on outpatient blood pressure management in Japan

K. Kobayashi, K. Chin, et al.

Listen, Learn & Level Up
Over 10,000 hours of research content in 25+ fields, available in 12+ languages.
No more digging through PDFs, just hit play and absorb the world's latest research in your language, on your time.
listen to research audio papers with researchbunny