This article analyzes the mortality burden of the COVID-19 pandemic across 569 regions in 25 European countries in 2020 and 2021, using age and sex-specific excess mortality data and Age-Standardised Years of Life Lost (ASYLL). A forecasting approach based on CP-splines revealed significant losses in most regions, with a shift in geographical patterns from initial outbreak areas to an East-West gradient in 2021. The study highlights the importance of regional analyses for understanding the pandemic's impact.
Publisher
Nature Communications
Published On
May 18, 2024
Authors
Florian Bonnet, Pavel Grigoriev, Markus Sauerberg, Ina Alliger, Michael Mühlichen, Carlo-Giovanni Camarda
Tags
COVID-19
mortality burden
excess mortality
Age-Standardised Years of Life Lost
regional analysis
geographical patterns
European countries
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