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Single-cell transcriptomics of human iPSC differentiation dynamics reveal a core molecular network of Parkinson's disease

Medicine and Health

Single-cell transcriptomics of human iPSC differentiation dynamics reveal a core molecular network of Parkinson's disease

G. Novak, D. Kyriakis, et al.

Explore the groundbreaking findings from a study by Gabriela Novak and colleagues, which reveals a converging network for Parkinson's disease pathways using midbrain dopaminergic neurons derived from human induced pluripotent stem cells. This research uncovers significant alterations in gene expression and dopamine metabolism, potentially enhancing our understanding of the disease's phenotypic heterogeneity.

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