Veterinary ScienceCommunications Biology
Single-cell RNA sequencing reveals the cellular and molecular heterogeneity of treatment-naïve primary osteosarcoma in dogs
D. T. Ammons, L. S. Hopkins, et al.
Discover groundbreaking insights into osteosarcoma, an aggressive bone cancer, through single-cell RNA sequencing in treatment-naïve dogs. This research, conducted by Dylan T. Ammons, Leone S. Hopkins, Kathryn E. Cronise, Jade Kurihara, Daniel P. Regan, and Steven Dow, reveals 41 distinct cell types and underscores the translational potential of canine models in immuno-oncology.
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