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Shifted balance between ventral striatal prodynorphin and proenkephalin biases development of cocaine place avoidance

Psychology

Shifted balance between ventral striatal prodynorphin and proenkephalin biases development of cocaine place avoidance

A. Nicot, P. Yecham, et al.

Research by Amellia Nicot, Pavankumar Yecham, Ilana Serin, David J Barker, and Lauren K Dobbs explores how cocaine can trigger aversive states in mice. This study uncovers key insights into the role of striatal opioid peptides in shaping these responses, revealing intriguing correlations between dynorphin levels and conditioned place avoidance. Discover the potential implications for understanding addiction and withdrawal effects!... show more
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