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Serial monitoring of circulating tumour DNA on clinical outcome in myelodysplastic syndromes and acute myeloid leukaemia

Medicine and Health

Serial monitoring of circulating tumour DNA on clinical outcome in myelodysplastic syndromes and acute myeloid leukaemia

X. Zhou, W. Lang, et al.

This groundbreaking study by Xinping Zhou and colleagues reveals that circulating tumor DNA (ctDNA) is a promising minimally invasive biomarker for monitoring treatment outcomes in myelodysplastic syndromes and acute myeloid leukemia. The findings highlight the significant correlation between ctDNA concentrations and tumor burden, underscoring its potential in predicting patient survival and detecting early relapses.

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~3 min • Beginner • English
Abstract
Publisher
Clinical and Translational Medicine
Published On
Jul 20, 2023
Authors
Xinping Zhou, Wei Lang, Chen Mei, Yanling Ren, Liya Ma, Lingxu Jiang, Li Ye, Gaixiang Xu, Yingwan Luo, Lixia Liu, Shanbo Cao, Jiayue Qin, Hongyan Tong
Tags
circulating tumor DNA
myelodysplastic syndromes
acute myeloid leukemia
biomarker
prognosis
clonal evolution
treatment monitoring

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