Scalable batch fabrication of ultrathin flexible neural probes | ResearchBunny

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Abstract

This paper presents a novel scalable batch fabrication approach for ultrathin and flexible neural probes. The probes consist of a silk-parylene bilayer, where the biodegradable silk layer acts as a temporary stiffener for insertion, enabling the use of ultrathin parylene-based flexible devices. This method allows for control over probe design and has shown successful ex vivo insertion with high-fidelity recordings of epileptic seizures and single-unit action potentials in mouse brain slices.

Publisher

Microsystems & Nanoengineering

Published On

Jan 28, 2022

Authors

Clement Cointe, Adrian Laborde, Lionel G. Nowak, Dina N. Arvanitis, David Bourrier, Christian Bergaud, Ali Maziz

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