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SARS-CoV-2 infection of human lung epithelial cells induces TMPRSS-mediated acute fibrin deposition

Medicine and Health

SARS-CoV-2 infection of human lung epithelial cells induces TMPRSS-mediated acute fibrin deposition

R. Erickson, C. Huang, et al.

Discover groundbreaking research by Rachel Erickson and colleagues on a novel fibrin clotting mechanism linked to severe COVID-associated lung injury. This study reveals how SARS-CoV-2 infection in primary lung cells triggers fibrin formation and highlights the limitations of current anticoagulation treatments, making a compelling case for developing new therapeutic strategies.

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