Medicine and Health

Recent progress in the development of nanomaterials targeting multiple cancer metabolic pathways: a review of mechanistic approaches for cancer treatment

L. Zhang, B. Zhai, et al.

Explore groundbreaking strategies in cancer therapy utilizing nanomaterials that target specific cancer metabolisms. This review showcases the superior advantages of nanoparticle-based therapies over traditional methods, while addressing the associated challenges and future prospects. This insightful research was conducted by Ling Zhang, Bing-Zhong Zhai, Yue-Jin Wu, and Yin Wang.

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~3 min • Beginner • English

Index

Abstract

Cancer cells reprogram metabolism to meet demands for energy, biosynthetic precursors, and redox balance. Given the centrality of metabolic pathways to tumor growth and transformation, targeting metabolism offers promising, more specific cancer treatments with reduced side effects. Nanomaterials that exploit metabolic vulnerabilities are emerging as powerful therapeutic options. This review summarizes cutting‑edge nanomaterial strategies that target multiple cancer metabolic pathways, contrasts nanoparticle (NP)-based therapies with conventional treatments, and discusses current challenges and future prospects.

Publisher

Drug Delivery

Published On

Jan 01, 2023

Authors

Ling Zhang, Bing-Zhong Zhai, Yue-Jin Wu, Yin Wang

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