Medicine and Health

Recent advances in immunotherapy and molecular targeted therapy for gastric cancer

Y. Yoshinami and H. Shoji

Gastric cancer remains a major global health challenge, with limited survival rates despite advances in therapy. This exciting review by Yuri Yoshinami and Hirokazu Shoji investigates the latest breakthroughs in immunotherapy and molecular targeted therapies, highlighting the promising role of immune checkpoint inhibitors and their combinations with other treatment approaches.

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Playback language: English

Index

Abstract

Gastric cancer is a significant global health concern, ranking fourth in both incidence and mortality. Despite advancements in chemotherapy, median survival remains limited (12-15 months). This review examines recent progress in immunotherapy and molecular targeted therapies for gastric cancer, focusing on immune checkpoint inhibitors (ICIs) and their combinations with cytotoxic and targeted agents. Clinical trials demonstrate potential benefits, particularly with anti-PD-1/PD-L1 inhibitors, and ongoing research explores combination strategies to improve outcomes.

Publisher

Future Science OA

Published On

Mar 17, 2023

Authors

Yuri Yoshinami, Hirokazu Shoji

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