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Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis

Medicine and Health

Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis

A. Shannon, B. Selisko, et al.

This research reveals how Favipiravir exerts its antiviral effects against SARS-CoV-2 through lethal mutagenesis, inducing genomic instability and viral inhibition. Conducted by a team of experts including Ashleigh Shannon and Barbara Selisko, this study highlights the importance of viral RNA incorporation rates in combating the virus.... show more
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