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Abstract
Limited data exists on the persistence of neutralizing antibodies (NAbs) among SARS-CoV-2-infected healthcare workers (HCW). This study followed 26 HCW with mild COVID-19, assessing NAbs at three time points. A significant decrease in NAb titers was observed over time, correlating with a decline in systemic IgA antibody levels. This short-lived humoral protection highlights the need for continued infection prevention measures and potential periodic vaccination boosts for HCW.
Publisher
Nature Communications
Published On
Feb 08, 2021
Authors
Stéphane Marot, Isabelle Malet, Valentin Leduc, Karen Zafilaza, Delphine Sterlin, Delphine Planas, Adèle Gonthald, Aude Jary, Karim Dorgham, Timothée Bruel, Sonia Burrel, David Boutolleau, Olivier Schwartz, Guy Gorochov, Vincent Calvez, Anne-Geneviève Marcelin
Tags
SARS-CoV-2
neutralizing antibodies
healthcare workers
COVID-19
immunity
vaccination
infection prevention

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