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Quantum Microscopy of Cells at the Heisenberg Limit

Medicine and Health

Quantum Microscopy of Cells at the Heisenberg Limit

Z. He, Y. Zhang, et al.

Discover the groundbreaking advancements in quantum microscopy by coincidence (QMC) achieved by Zhe He and colleagues. This innovative technique utilizes entangled photons to break the barriers of super-resolution imaging, allowing for non-destructive bioimaging with a resolution of 1.4 µm in cancer cells. Experience imaging at the Heisenberg limit with unparalleled speed and contrast-to-noise ratio!

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Playback language: English
Abstract
This paper introduces quantum microscopy by coincidence (QMC) with balanced pathlengths, achieving super-resolution imaging at the Heisenberg limit. QMC utilizes entangled photons, where the balanced pathlengths in a symmetric configuration allow the photon pair to behave like a single photon with half the wavelength, doubling the resolution. The method demonstrates significantly improved speed and contrast-to-noise ratio (CNR) compared to existing wide-field quantum imaging techniques, along with substantially increased resistance to stray light. Experiments on cancer cells demonstrate a resolution of 1.4 µm, showcasing the potential for non-destructive bioimaging.
Publisher
Nature Communications
Published On
Apr 28, 2023
Authors
Zhe He, Yide Zhang, Xin Tong, Lei Li, Lihong V. Wang
Tags
quantum microscopy
super-resolution imaging
Heisenberg limit
entangled photons
bioimaging
cancer cells
contrast-to-noise ratio
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