logo
ResearchBunny Logo
Preparation of glass-ionomer cement containing ethanolic Brazilian pepper extract (*Schinus terebinthifolius* Raddi) fruits: chemical and biological assays

Medicine and Health

Preparation of glass-ionomer cement containing ethanolic Brazilian pepper extract (*Schinus terebinthifolius* Raddi) fruits: chemical and biological assays

I. C. Pinto, J. B. Seibert, et al.

This innovative study presents a groundbreaking composite drug delivery system, combining glass-ionomer and Brazilian pepper extract, designed to combat oral pathogenic microorganisms while ensuring *in vitro* biocompatibility. Conducted by a team of researchers including Isabelle C. Pinto and Janaína B. Seibert, this research suggests a promising new alternative for endodontic treatment.

00:00
00:00
Playback language: English
Abstract
This study aimed to prepare and evaluate a new drug delivery system based on a glass-ionomer-Brazilian pepper extract composite, to check for its activity against pathogenic microorganisms of the oral cavity, along with its *in vitro* biocompatibility. The ethanolic Brazilian pepper extract (BPE), the glass-ionomer cement (GIC) and the composite GIC-BPE were characterized. The flavonoids were released through a linear mechanism governing the diffusion for the first 48 h. ATR-FTIR analysis indicated a chemical bond between GIC and BPE, but compressive strength did not differ significantly. The GIC-BPE sample showed ample bacterial activity at non-cytotoxic concentrations. These results suggest the composite as an alternative agent for endodontic treatment.
Publisher
Scientific Reports
Published On
Dec 18, 2020
Authors
Isabelle C. Pinto, Janaína B. Seibert, Luciano S. Pinto, Vagner R. Santos, Rafaela F. de Sousa, Lucas R. D. Sousa, Tatiane R. Amparo, Viviane M. R. dos Santos, Andrea M. do Nascimento, Gustavo Henrique Bianco de Souza, Walisson A. Vasconcellos, Paula M. A. Vieira, Angela L. Andrade
Tags
drug delivery system
glass-ionomer
Brazilian pepper extract
oral cavity
biocompatibility
pathogenic microorganisms
endodontic treatment

Related Publications

Explore these studies to deepen your understanding of the subject.

Substantial loss of isoprene in the surface ocean due to chemical and biological consumption
Earth Sciences

Substantial loss of isoprene in the surface ocean due to chemical and biological consumption

R. Simó, P. Cortés-greus, et al.

Effects of gelatin type and concentration on the preparation and properties of freeze-dried fish oil powders
Food Science and Technology

Effects of gelatin type and concentration on the preparation and properties of freeze-dried fish oil powders

M. Yang, J. Peng, et al.

Postprandial glycemic and lipidemic effects of black rice anthocyanin extract fortification in foods of varying macronutrient compositions and matrices
Food Science and Technology

Postprandial glycemic and lipidemic effects of black rice anthocyanin extract fortification in foods of varying macronutrient compositions and matrices

S. J. L. Ou, D. Yang, et al.

In situ analysis of the bulk and surface chemical compositions of organic aerosol particles
Chemistry

In situ analysis of the bulk and surface chemical compositions of organic aerosol particles

Y. Qian, J. B. Brown, et al.

Listen, Learn & Level Up
Over 10,000 hours of research content in 25+ fields, available in 12+ languages.
No more digging through PDFs, just hit play and absorb the world's latest research in your language, on your time.
listen to research audio papers with researchbunny