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Inhibitory and preventive effects of *Arnebia euchroma* (Royle) Johnst. root extract on *Streptococcus mutans* and dental caries in rats

Medicine and Health

Inhibitory and preventive effects of *Arnebia euchroma* (Royle) Johnst. root extract on *Streptococcus mutans* and dental caries in rats

Z. Wu, J. Song, et al.

This exciting study by Zeyu Wu, Jie Song, Yangyang Zhang, Xiyu Yuan, and Jin Zhao reveals the powerful antibacterial properties of *Arnebia euchroma* root extract against *Streptococcus mutans*, showcasing its potential in preventing and treating dental caries with excellent biosafety. Discover how this natural solution could change dental care!

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Playback language: English
Abstract
This study investigated the antibacterial effect of *Arnebia euchroma* (Royle) Johnst. root (AR) extract on *Streptococcus mutans* (*S. mutans*) UA159 and its anti-caries effect on rats. AR extract inhibited *S. mutans* growth and biofilm formation, and reduced bacterial adhesion to hydroxyapatite. In a rat caries model, AR extract significantly reduced caries incidence and severity, demonstrating excellent biosafety. These findings suggest AR extract's potential for dental caries prevention and treatment.
Publisher
BDJ Open
Published On
Mar 02, 2024
Authors
Zeyu Wu, Jie Song, Yangyang Zhang, Xiyu Yuan, Jin Zhao
Tags
Arnebia euchroma
Streptococcus mutans
antibacterial effect
dental caries
biofilm formation
caries prevention
biosafety

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