Inhibitory and preventive effects of *Arnebia euchroma* (Royle)

Index

Abstract

This study investigated the antibacterial effect of *Arnebia euchroma* (Royle) Johnst. root (AR) extract on *Streptococcus mutans* (*S. mutans*) UA159 and its anti-caries effect on rats. AR extract inhibited *S. mutans* growth and biofilm formation, and reduced bacterial adhesion to hydroxyapatite. In a rat caries model, AR extract significantly reduced caries incidence and severity, demonstrating excellent biosafety. These findings suggest AR extract's potential for dental caries prevention and treatment.

Publisher

BDJ Open

Published On

Mar 02, 2024

Authors

Zeyu Wu, Jie Song, Yangyang Zhang, Xiyu Yuan, Jin Zhao

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