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Prefrontal Cortex-Specific Knockdown of Neurexin-1 in Rats Induces Anxiety-Like Behavior, Repetitive Behaviors, and Altered Social Interactions: A Proteomic Study

Biology

Prefrontal Cortex-Specific Knockdown of Neurexin-1 in Rats Induces Anxiety-Like Behavior, Repetitive Behaviors, and Altered Social Interactions: A Proteomic Study

D. Wu, S. Zhang, et al.

This groundbreaking study by D Wu, S Zhang, Q Xu, L You, J Zhu, J Wang, and Y Li reveals the vital role of Neurexin-1 in the prefrontal cortex of rats, linking its knockdown to anxiety-like behaviors and significant changes in neuronal morphology. Discover how these findings could shed light on neurodevelopmental disorders!... show more
Abstract
Publisher
Journal of Neurodevelopmental Disorders
Published On
Mar 01, 2023
Authors
D Wu, S Zhang, Q Xu, L You, J Zhu, J Wang, Y Li
Tags
Neurexin-1
knockdown
prefrontal cortex
anxiety-like behavior
neuronal morphology
proteomic analysis
neurodevelopmental disorders

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