Medicine and Health

Pneumonitis in Non-Small Cell Lung Cancer Patients Receiving Atezolizumab Post Chemo-Radiation

L. J. Saade and A. Tfayli

This study reveals a significant risk of pneumonitis in stage III NSCLC patients receiving Atezolizumab following chemoradiation, with 8 out of 14 patients affected. Conducted by Lili Jose Saade and Arafat Tfayli, the findings raise concerns about treatment implications and the need for larger studies.

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Abstract

This study investigated the incidence and severity of pneumonitis in stage III NSCLC patients receiving Atezolizumab as consolidation therapy after concurrent chemoradiation. Of 14 patients, 8 developed pneumonitis. Age, gender, and smoking status did not significantly affect pneumonitis risk. Histology may be a factor, with a higher incidence in squamous cell carcinoma, although this was not statistically significant due to the small sample size. The study highlights the significant risk of pneumonitis with Atezolizumab post chemoradiation and calls for larger studies.

Publisher

Asian Pacific Journal of Cancer Prevention

Published On

Mar 12, 2023

Authors

Lili Jose Saade, Arafat Tfayli

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