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Oncogenic p53 triggers amyloid aggregation of p63 and p73 liquid droplets

Medicine and Health

Oncogenic p53 triggers amyloid aggregation of p63 and p73 liquid droplets

E. C. Petronilho, G. C. D. Andrade, et al.

This groundbreaking study by Elaine C. Petronilho and colleagues reveals how mutant p53 drives p63 and p73 into amyloid-like states, forming membraneless organelles. Heparin has been identified as a potential inhibitor of this prion-like process. Discover the implications of these findings for cancer therapy!... show more
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91
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Note: The citation metrics presented here have been sourced from Semantic Scholar and OpenAlex.

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