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O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology
Medicine and HealthNature Chemical Biology

O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology

A. T. Balana, A. Mahul-mellier, et al.

Discover the groundbreaking research by Aaron T. Balana and colleagues that reveals how O-GlcNAc modification transforms α-synuclein monomers into amyloid fibrils with unique structures, impacting seeding activity in Parkinson's disease models. Their findings shed light on the role of post-translational modifications in determining pathogenicity.... show more
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Citations
80
Influential Citations
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Reference Count
70
Citation by Year

Note: The citation metrics presented here have been sourced from Semantic Scholar and OpenAlex.

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