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Novel microglial transcriptional signatures promote social and cognitive deficits following repeated social defeat

Medicine and Health

Novel microglial transcriptional signatures promote social and cognitive deficits following repeated social defeat

E. J. Goodman, D. J. Disabato, et al.

Discover how chronic stress triggers anxiety and cognitive decline through novel stress-associated microglia in the hippocampus, as revealed by cutting-edge single-cell technologies. This groundbreaking research, conducted by Ethan J. Goodman, Damon J. DiSabato, John F. Sheridan, and Jonathan P. Godbout, unveils the complex role of microglia in stress response, social withdrawal, and cognitive impairment.

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~3 min • Beginner • English
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