Medicine and Health

Metastability indexes global changes in the dynamic working point of the brain following brain stimulation

R. Bapat, A. Pathak, et al.

New analysis shows single-pulse TMS transiently reduces brain metastability and increases coherence, defining a measurable window of altered neural coordination; higher EEG frequencies recover faster and Lempel‑Ziv complexity confirms reduced dynamical complexity. Using public datasets and a whole‑brain digital twin, the study reveals how local phase resetting can propagate globally. This research was conducted by Rishabh Bapat, Anagh Pathak, and Arpan Banerjee.