Medicine and Health

Mega-oss and Mega-TCP versus Bio-Oss granules fixed by alginate gel for bone regeneration

T. Wang, S. Xu, et al.

Explore the exciting findings of Tong-Yue Wang, Shu-Lan Xu, Zhi-Ping Wang, and Jin-Yuan Guo, who evaluated innovative bone substitutes Mega-oss and Mega-TCP against Bio-Oss. Their research reveals superior cell spreading and promising viability, suggesting that these new materials could be viable alternatives in the world of bone substitutes.

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Abstract

This study compared the biocompatibility of new bone substitutes, Mega-oss and Mega-TCP, with Bio-Oss using osteoblast and osteoclast cells fixed with alginate gel. Results showed better cell spreading on Mega-oss and Mega-TCP than on Bio-Oss. MTT assays indicated good viability for all materials, with Mega-oss and Mega-TCP showing similar osteoblast differentiation ability to Bio-Oss. Mega-TCP and Mega-oss exhibited higher resorption rates than Bio-Oss. The authors conclude that Mega-oss and Mega-TCP may be viable alternatives to Bio-Oss, and that alginate gel fixation is a useful method for in vitro bone material experiments.

Publisher

BDJ Open

Published On

Aug 11, 2020

Authors

Tong-Yue Wang, Shu-Lan Xu, Zhi-Ping Wang, Jin-Yuan Guo

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