Veterinary Science

Longitudinal evaluation of fecal microbiota transplantation for ameliorating calf diarrhea and improving growth performance

H. S. Kim, T. W. Whon, et al.

Calf diarrhea poses a major risk in livestock management, often requiring antibiotic intervention. This groundbreaking research by Hyun Sik Kim and colleagues investigates fecal microbiota transplantation (FMT) as a viable alternative, demonstrating its potential to alleviate diarrhea and improve calf growth performance over two years. Discover the promising outcomes that could reshape treatment approaches in veterinary science!

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Playback language: English

Index

Abstract

Calf diarrhea is a significant challenge in livestock production, often necessitating antibiotic use with associated risks. This study evaluated fecal microbiota transplantation (FMT) as an alternative treatment in 57 growing calves. Multi-omics analysis of 450 fecal samples revealed that FMT increased *Porphyromonadaceae* and reduced fecal amino acid concentrations, correlating with diarrhea remission. Over 24 months, FMT improved cattle growth performance. This first ruminant FMT trial suggests FMT's potential for treating calf diarrhea and enhancing growth.

Publisher

NATURE COMMUNICATIONS

Published On

Jan 08, 2021

Authors

Hyun Sik Kim, Tae Woong Whon, Hojun Sung, Yun-Seok Jeong, Eun Sung Jung, Na-Ri Shin, Dong-Wook Hyun, Pil Soo Kim, June-Young Lee, Choong Hwan Lee, Jin-Woo Bae

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