Calf diarrhea is a significant challenge in livestock production, often necessitating antibiotic use with associated risks. This study evaluated fecal microbiota transplantation (FMT) as an alternative treatment in 57 growing calves. Multi-omics analysis of 450 fecal samples revealed that FMT increased *Porphyromonadaceae* and reduced fecal amino acid concentrations, correlating with diarrhea remission. Over 24 months, FMT improved cattle growth performance. This first ruminant FMT trial suggests FMT's potential for treating calf diarrhea and enhancing growth.
Publisher
NATURE COMMUNICATIONS
Published On
Jan 08, 2021
Authors
Hyun Sik Kim, Tae Woong Whon, Hojun Sung, Yun-Seok Jeong, Eun Sung Jung, Na-Ri Shin, Dong-Wook Hyun, Pil Soo Kim, June-Young Lee, Choong Hwan Lee, Jin-Woo Bae
Tags
calf diarrhea
fecal microbiota transplantation
antibiotic alternative
growth performance
livestock health
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