Medicine and HealthNature Communications
Intracranial directed connectivity links subregions of the prefrontal cortex to major depression
J. Myers, J. Xiao, et al.
Intracranial recordings from prefrontal subregions reveal that major depressive disorder involves cortical disinhibition: delta-band directed connectivity rises during negative mood and symptom severity tracks left–right prefrontal imbalance. Research conducted by John Myers, Jiayang Xiao, Raissa K. Mathura, Ben Shofty, Victoria Gates, Joshua Adkinson, Anusha B. Allawala, Adrish Anand, Ron Gadot, Ricardo Najera, Hernan G. Rey, Sanjay J. Mathew, Kelly Bijanki, Garrett Banks, Andrew Watrous, Eleonora Bartoli, Sarah R. Heilbronner, Nicole Provenza, Wayne K. Goodman, Nader Pouratian, Benjamin Y. Hayden, and Sameer A. Sheth.
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