Psychology
Intermittent rate coding and cue-specific ensembles support working memory
M. F. Panichello, D. Jonikaitis, et al.
This groundbreaking study by Matthew F. Panichello and colleagues reveals that working memory in the lateral prefrontal cortex doesn't rely solely on persistent spiking activity. Instead, it alternates between 'On' and 'Off' states, fundamentally changing our understanding of mnemonic processes. During 'Off' states, neuronal selectivity fades, yet information is maintained through unique functional connections. Discover how working memory is a dance between spiking and synaptic mechanisms.
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