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Inflammatory Molecule Profiles in Preschool Children with Neurodevelopmental Disorders Secondary to Perinatal Risks

Biology

Inflammatory Molecule Profiles in Preschool Children with Neurodevelopmental Disorders Secondary to Perinatal Risks

M. M, B. M, et al.

This groundbreaking study by Madrid M and colleagues explores the intriguing connection between inflammatory molecule profiles and neurological disorders in preschoolers facing perinatal risks. Discover how these scientists unveil distinct inflammatory patterns and a unique 'hyper-resolution' state in at-risk children, offering insights into complex biological responses.

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Playback language: English
Abstract
This study investigated the association between inflammatory molecule profiles and various expressions of neurological disorders in preschool children with a history of perinatal risks. The findings revealed distinct and even opposing inflammatory profiles associated with different neurological alterations, suggesting complex molecular adjustments to challenges, damage, and sequelae. A "hyper-resolution" state, characterized by low pro- and anti-inflammatory molecules and high pro-resolving mediators, was observed in children at high risk for regulatory disorders.
Publisher
Frontiers in Pediatrics
Published On
Apr 20, 2023
Authors
Madrid M, Brianza-Padilla M, Zapoteco-Nava J, Márquez-Velasco R, Rivera-González R, Gonzalez-Perez G, Du J, Hernández M, Bojalil R
Tags
inflammatory molecules
neurological disorders
preschool children
perinatal risks
molecular adjustments
regulatory disorders
hyper-resolution state
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