Pediatric laryngotracheal stenosis is a complex airway injury requiring various treatments. A biodegradable airway stent could offer a less invasive solution. This study demonstrates the in-vivo efficacy of an ultra-high ductility magnesium-alloy stent, showing high corrosion resistance and safe degradation without affecting airway growth in rabbits. The stent was well-tolerated, exhibiting no toxicity.
Publisher
Communications Biology
Published On
Dec 18, 2020
Authors
Jingyao Wu, Leila J. Mady, Abhijit Roy, Ali Mübin Aral, Boeun Lee, Feng Zheng, Toma Catalin, Youngjae Chun, William R. Wagner, Ke Yang, Humberto E. Trejo Bittar, David Chi, Prashant N. Kumta
Tags
pediatric laryngotracheal stenosis
biodegradable airway stent
magnesium-alloy stent
corrosion resistance
airway growth
in-vivo efficacy
safe degradation
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