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Human Brain Organoids-on-Chip: Advances, Challenges, and Perspectives for Preclinical Applications

Medicine and Health

Human Brain Organoids-on-Chip: Advances, Challenges, and Perspectives for Preclinical Applications

H. Castiglione, P. Vigneron, et al.

Cerebral organoids coupled with microfluidic "brain-on-chip" systems promise reproducible, high-quality models of the human brain for disease modeling and drug discovery. This review — conducted by Héloïse Castiglione, Pierre-Antoine Vigneron, Camille Baquerre, Frank Yates, Jessica Rontard, and Thibault Honegger — explains how organoids-on-chips boost maturation, reproducibility, and compatibility with high-throughput pharmacological screens.

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~3 min • Beginner • English
Citation Metrics
Citations
37
Influential Citations
1
Reference Count
78
Citation by Year

Note: The citation metrics presented here have been sourced from Semantic Scholar and OpenAlex.

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