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How side effects can improve treatment efficacy: a randomized trial

Medicine and Health

How side effects can improve treatment efficacy: a randomized trial

L. A. Schenk, T. Fadai, et al.

This study by Lieven A. Schenk, Tahmine Fadai, and Christian Büchel explores how mild side effects can positively influence treatment outcomes by altering expectations. Participants experiencing nasal sprays believed to contain fentanyl reported reduced pain when side effects were involved, suggesting that expectations play a pivotal role in pain perception. The research reveals intriguing insights into the brain's pain modulation mechanisms.

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