This paper presents a high-performance triboelectric-electromagnetic hybrid nanogenerator (TEHNG) for self-powered wireless multi-sensing microsystems. The TEHNG achieves a high load power of 21.8 mW through material and configuration optimization and a pyramid microstructure design. An integrated microsystem incorporating power management, energy storage, sensing signal processing, and a microcontroller unit is developed. This system, incorporating temperature, pressure, and UV sensors, operates continuously, wirelessly transmitting data in real-time using the TEHNG as the sole power source. This demonstrates significant potential for IoT applications.