Medicine and Health

Global warming and testis function: A challenging crosstalk in an equally challenging environmental scenario

L. D. Toni, F. Finocchi, et al.

This captivating review by Luca De Toni, Federica Finocchi, Kenda Jawich, and Alberto Ferlin delves into how global warming impacts male fertility and testis function. It uncovers physiological mechanisms, examines heat stress effects on spermatogenesis, and evaluates epidemiological studies, highlighting the challenges of establishing a causal link.

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Playback language: English

Index

Abstract

This review examines the impact of environmental temperature, particularly global warming, on male fertility and testis function. It explores the physiological mechanisms of testicular thermoregulation, the effects of heat stress on spermatogenesis and steroidogenesis using both animal and human models, and critically evaluates epidemiological studies examining the association between global warming and declining testis function. The review highlights the complexities of establishing a direct causal link and identifies key methodological challenges.

Publisher

Frontiers in Cell and Developmental Biology

Published On

Oct 26, 2022

Authors

Luca De Toni, Federica Finocchi, Kenda Jawich, Alberto Ferlin

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