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Exploiting the aggregation propensity of beta-lactamases to design inhibitors that induce enzyme misfolding

Medicine and Health

Exploiting the aggregation propensity of beta-lactamases to design inhibitors that induce enzyme misfolding

L. Khodaparast, L. Khodaparast, et al.

This groundbreaking research conducted by Ladan Khodaparast, Laleh Khodaparast, and their colleagues reveals a novel approach to combat antibiotic resistance via the aggregation of beta-lactamases. By utilizing synthetic peptides to induce enzyme misfolding, the study paves the way for restoring antibiotic sensitivity in resistant strains, addressing a pressing global health crisis.... show more
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Citations
10
Influential Citations
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Reference Count
60
Citation by Year

Note: The citation metrics presented here have been sourced from Semantic Scholar and OpenAlex.

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