Agriculture

Transfer of cannabinoids into the milk of dairy cows fed with industrial hemp could lead to Δ⁹-THC exposure that exceeds acute reference dose

B. Wagner, P. Gerletti, et al.

This groundbreaking study reveals the transfer of cannabinoids from industrial hemp silage to dairy cow milk, highlighting significant levels of Δ⁹-THC that pose concerns for human health. Conducted by Bettina Wagner, Pietro Gerletti, and their team, the research uncovers not only these health risks but also adverse effects on the cows, making it essential reading for anyone interested in agricultural safety and animal welfare.

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Playback language: English

Index

Abstract

This study investigated the transfer of cannabinoids from industrial hemp silage into the milk of dairy cows. Feeding hemp silage resulted in measurable levels of various cannabinoids in cow's milk, with Δ⁹-THC levels exceeding the acute reference dose (ARfD) for humans in several consumer groups under certain exposure scenarios. The study also observed negative effects on animal health, including decreased feed intake and milk yield, and changes in respiratory and heart rates. A toxicokinetic model was developed to predict cannabinoid transfer, and a new analytical method was used to differentiate between Δ⁹-THC and its non-psychoactive precursor, Δ⁹-THCA.

Publisher

Nature Food

Published On

Nov 14, 2022

Authors

Bettina Wagner, Pietro Gerletti, Peter Fürst, Oliver Keuth, Thorsten Bernsmann, Annett Martin, Bernd Schäfer, Jorge Numata, Marc C. Lorenzen, Robert Pieper

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