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Explainable machine learning identifies multi-omics signatures of muscle response to spaceflight in mice

Space Sciences

Explainable machine learning identifies multi-omics signatures of muscle response to spaceflight in mice

K. Li, R. Desai, et al.

This groundbreaking study explores how spaceflight triggers muscle atrophy in mice by unraveling the mysteries of calcium dysregulation and SERCA pump malfunction. The innovative use of multi-omics data highlights Acyp1 and Rps7 as pivotal proteins linked to muscle resilience in microgravity. This research, conducted by Kevin Li and colleagues, offers crucial insights for mitigating muscle loss during space travel.

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