Medicine and Health

Exclusive Human Milk Diet for Extremely Premature Infants: A Novel Fortification Strategy That Enhances the Bioactive Properties of Fresh, Frozen, and Pasteurized Milk Specimens

R. K. Philip, E. Romeih, et al.

Discover how researchers Roy K Philip, Ehab Romeih, Elizabeth Bailie, Mandy Daly, Kieran D Mcgourty, Andreas M Grabrucker, Colum P Dunne, and Gavin Walker analyzed the bioactive components of human milk, revealing that donor human milk falls short in fortification compared to mothers' own milk. They found that freshly expressed milk fortified with a human milk-derived fortifier may offer the best nutrition for extremely premature infants.

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Abstract

This study analyzed the bioactive components of human milk (HM) and evaluated fortification choices to optimize nutrition for extremely premature infants. Donor human milk (DHM) showed lower lactoferrin and α-lactalbumin than mothers' own milk (MOM). Human milk-derived fortifier (HMDF) reinstated these components and enhanced antioxidant activity compared to cow's milk-derived fortifier (CMDF). Freshly expressed MOM fortified with HMDF is suggested as an optimal nutritional choice.

Publisher

Breastfeeding Medicine

Published On

Jan 01, 2023

Authors

Roy K Philip, Ehab Romeih, Elizabeth Bailie, Mandy Daly, Kieran D Mcgourty, Andreas M Grabrucker, Colum P Dunne, Gavin Walker

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