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Evaluating cancer etiology and risk with a mathematical model of tumor evolution
Medicine and HealthNature Communications

Evaluating cancer etiology and risk with a mathematical model of tumor evolution

S. Pénisson, A. Lambert, et al.

This research by Sophie Pénisson, Amaury Lambert, and Cristian Tomasetti unveils a groundbreaking mathematical model that predicts the expected number of innate somatic mutations in tissues as we age. By correlating these predictions with actual observations, the study reveals that these mutational processes account for a staggering 80% of the variability in cancer risk, underscoring their critical role in understanding cancer development.... show more
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