Medicine and Health

Efficacy of green jackfruit flour as a medical nutrition therapy replacing rice or wheat in patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled study

A. G. Rao, K. S. Naik, et al.

This exciting study by Gopal Rao et al. explored the potential of Jackfruit365™ green jackfruit flour in managing type 2 diabetes. With 40 patients participating in a 12-week trial, results showed significant reductions in HbA1c and glucose levels, providing promising evidence for jackfruit flour as a healthy alternative to traditional flour in diabetic diets.

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Abstract

This randomized, double-blind, placebo-controlled study evaluated the efficacy of Jackfruit365™ green jackfruit flour in managing type 2 diabetes mellitus (T2DM). 40 patients received either jackfruit flour (30g/day) or placebo flour for 12 weeks, replacing an equal volume of rice or wheat flour in their daily meals. The primary endpoint was mean change in glycosylated hemoglobin (HbA1c). Group A (jackfruit flour) showed significantly higher reductions in HbA1c (-2.73 mmol/mol), fasting plasma glucose (FPG), and postprandial plasma glucose (PPG) compared to Group B (placebo). Continuous glucose monitoring confirmed lower blood glucose levels in the jackfruit flour group. The study concludes that jackfruit flour is effective in glycemic control as a medical nutrition therapy replacement for rice or wheat flour in T2DM patients.

Publisher

Nutrition & Diabetes

Published On

Jun 14, 2021

Authors

A. Gopal Rao, K. Sunil Naik, A. G. Unnikrishnan, James Joseph

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