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Efficacy of early PET-CT directed switch to carboplatin and paclitaxel based definitive chemoradiotherapy in patients with oesophageal cancer who have a poor early response to induction cisplatin and capecitabine in the UK: a multi-centre randomised controlled phase II trial

Medicine and Health

Efficacy of early PET-CT directed switch to carboplatin and paclitaxel based definitive chemoradiotherapy in patients with oesophageal cancer who have a poor early response to induction cisplatin and capecitabine in the UK: a multi-centre randomised controlled phase II trial

S. Mukherjee, C. N. Hurt, et al.

This groundbreaking multi-center trial explored how early PET-CT scans could guide chemotherapy choices in oesophageal cancer patients. Conducted by a team including Somnath Mukherjee and Christopher N Hurt among others, the study revealed that switching treatment may not be beneficial. Findings suggest a need to reassess early metabolic response assessment in guiding therapy, especially for oesophageal squamous cell carcinoma.

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