Food Science and Technologynpj Science of Food

Effects of high fructose corn syrup on intestinal microbiota structure and obesity in mice

X. Wang, L. Zhu, et al.

This fascinating study by Xiaorong Wang and colleagues explores how high fructose corn syrup influences body fat and gut microbiome in mice, revealing significant increases in body fat and notable changes in gut microbiota composition. Their findings highlight the intricate relationship between diet and health.... show more

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Abstract

High fructose corn syrup (HFCS)-associated health problems have raised concerns. We investigated the effects of HFCS-containing drinking water on body fat, intestinal microbiota structure of mice, and the relationships between them. HFCS drinking water significantly increased body fat content and altered the intestinal microbiome. The Christensenellaceae R-7 group negatively correlated with body weight, perirenal fat, epididymal fat, and liver fat percentage.

Publisher

npj Science of Food

Published On

Authors

Xiaorong Wang, Liying Zhu, Xiaoqiong Li, Xin Wang, Ruirong Hao, Jinjun Li

DOI

https://doi.org/10.1038/s41538-022-00133-7

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