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Abstract
This study investigates the associations between adherence to Mediterranean diet (MedDiet) or MIND diet and overall/specific cancer risks, exploring the mediating effects of metabolites using UK Biobank data. Results show significant negative associations of both diets with overall and several specific cancers. A sequential analysis identified 10 metabolites associated with cancer risk, mediating the relationship between diet and cancer risk. These findings highlight the complex interplay between diet, metabolites, and cancer development.
Publisher
Nature Communications
Published On
Jul 13, 2024
Authors
Yi Fan, Chanchan Hu, Xiaoxu Xie, Yanfeng Weng, Chen Chen, Zhakoun Wang, Xueqiong He, Dongxia Jiang, Shaodan Huang, Zhijian Hu, Fengqing Liu
Tags
Mediterranean diet
MIND diet
cancer risk
metabolites
UK Biobank
diet and health
nutritional epidemiology

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