Psychology
Dopamine release and dopamine-related gene expression in the amygdala are modulated by the gastrin-releasing peptide in opposite directions during stress-enhanced fear learning and extinction
Y. Morishita, I. Fuentes, et al.
This study reveals the pivotal role of gastrin-releasing peptide (GRP) in the regulation of dopaminergic control during fear extinction. Conducted by an extensive team of researchers, findings indicate that GRP knockout mice exhibit intensified fear memory, shedding light on mechanisms linked to PTSD and the basolateral amygdala's interaction with dopamine circuits.
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