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Diversity in a dish: Leveraging organoids to reflect genetic ancestry and sex differences in health and disease

Medicine and Health

Diversity in a dish: Leveraging organoids to reflect genetic ancestry and sex differences in health and disease

F. E. A. Soussi, F. Piraino, et al.

This review highlights how integrating genetic ancestry and biological sex with human pluripotent stem cells and donor-specific organoids can improve treatment efficacy, reduce drug toxicity, and address health disparities through high-throughput pharmacogenomic screening. Research conducted by Fadoua El Abdellaoui Soussi, Francesco Piraino, Janine Scholefield, Sylke Hoehnel-Ka, and Magdalena Kasendra.

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~3 min • Beginner • English
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