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Discovery of a non-canonical prototype long-chain monoacylglycerol lipase through a structure-based endogenous reaction intermediate complex

Biology

Discovery of a non-canonical prototype long-chain monoacylglycerol lipase through a structure-based endogenous reaction intermediate complex

N. Pinotsis, A. Krüger, et al.

Explore the innovative research by Nikos Pinotsis and colleagues on the high-resolution structure of an orphan lipase in complex with a C18 monoacylglycerol ester. This groundbreaking study characterizes the enzyme's functionality and opens up exciting biotechnology applications through strategic modulation of enzyme-substrate interactions.

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