logo
ResearchBunny Logo
Abstract
Accelerated corneal crosslinking (A-CXL) is hampered by rapid stromal oxygen depletion at higher UVA intensities. This study developed biocompatible graphitic carbon nitride (g-C3N4) quantum dots (QDs) and riboflavin/g-C3N4 QDs composites (RF@g-C3N4 QDs) as oxygen self-sufficient platforms for A-CXL. Both showed excellent photocatalytic oxygen generation, high ROS yield, and biosafety. A-CXL using g-C3N4 QDs or RF@g-C3N4 QDs was superior to the standard RF A-CXL protocol, indicating enhanced corneal strengthening. This suggests potential application of g-C3N4 QDs in A-CXL for corneal ectasias.
Publisher
Nature Communications
Published On
Jun 29, 2024
Authors
Mei Yang, Tingting Chen, Xin Chen, Hongxian Pan, Guoli Zhao, Zhongxing Chen, Nan Zhao, Qianfang Ye, Ming Chen, Shenrong Zhang, Rongrong Gao, Keith M. Meek, Sally Hayes, Xiaowei Ma, Xin Li, Yue Wu, Yiming Zhang, Na Kong, Wei Tao, Xingtao Zhou, Jinhai Huang
Tags
Accelerated corneal crosslinking
Graphitic carbon nitride
Oxygen generation
Photocatalytic
Corneal strengthening
Biosafety
Quantum dots

Related Publications

Explore these studies to deepen your understanding of the subject.

A new scheme for low-carbon recycling of urban and rural organic waste based on carbon footprint assessment: A case study in China
Environmental Studies and Forestry

A new scheme for low-carbon recycling of urban and rural organic waste based on carbon footprint assessment: A case study in China

K. Zhou, Y. Li, et al.

A generative artificial intelligence framework based on a molecular diffusion model for the design of metal-organic frameworks for carbon capture
Chemistry

A generative artificial intelligence framework based on a molecular diffusion model for the design of metal-organic frameworks for carbon capture

H. Park, X. Yan, et al.

Development and implementation of personal learning environment-based writing for publication scaffolding platform for Ph.D. Students
Education

Development and implementation of personal learning environment-based writing for publication scaffolding platform for Ph.D. Students

X. Xu, J. Liu, et al.

Not-for-profit or for-profit? Research on the high-quality development path of private universities in China based on system dynamics
Education

Not-for-profit or for-profit? Research on the high-quality development path of private universities in China based on system dynamics

S. Duan, H. Yang, et al.

Listen, Learn & Level Up
Over 10,000 hours of research content in 25+ fields, available in 12+ languages.
No more digging through PDFs—just hit play and absorb the world's latest research in your language, on your time.
listen to research audio papers with researchbunny