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Designed peptides as nanomolar cross-amyloid inhibitors acting via supramolecular nanofiber co-assembly

Medicine and Health

Designed peptides as nanomolar cross-amyloid inhibitors acting via supramolecular nanofiber co-assembly

K. Taş, B. D. Volta, et al.

This groundbreaking research unveils how constrained peptides, designed to mimic the amyloid-β peptide, act as powerful nanomolar cross-amyloid inhibitors. Conducted by a team including Karin Taş and Beatrice Dalla Volta, the study reveals these peptides effectively suppress cross-seeding of toxic amyloids, pointing towards promising anti-amyloid drug options and novel nanomaterials.

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~3 min • Beginner • English
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