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Degree and site of chromosomal instability define its oncogenic potential

Medicine and Health

Degree and site of chromosomal instability define its oncogenic potential

W. H. Hoevenaaar, A. Janssen, et al.

This groundbreaking study by Wilma H.M. Hoevenaaar and colleagues reveals how chromosomal instability (CIN) levels influence tumor formation, particularly in early-onset adenoma development in the intestine. Their findings highlight not only the critical CIN range needed for tumor formation but also its tissue-specific effects in the distal colon and small intestine.

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~3 min • Beginner • English
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