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Abstract
This longitudinal study examined the associations of fat mass, lean mass, and blood pressure (BP) from childhood to young adulthood with changes in carotid-femoral pulse wave velocity (cfPWV) and carotid intima-media thickness (cIMT). Using data from 3863 participants in the Avon Longitudinal Study of Parents and Children, researchers found that cumulative high lean mass, systolic BP, and diastolic BP were positively associated with increased cfPWV. Persistent high lean mass, BMI, and systolic BP were associated with thicker cIMT. Total and trunk fat mass showed no association with cfPWV or cIMT progression. Increased lean mass and BP, but not fat mass, drive arterial remodeling in young adulthood.
Publisher
Springer Nature
Published On
Oct 14, 2022
Authors
Andrew O. Agbaje, Alan R. Barker, Tomi-Pekka Tuomainen
Tags
lean mass
blood pressure
carotid-femoral pulse wave velocity
carotid intima-media thickness
fat mass
longitudinal study
arterial remodeling

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