Cortical structural and functional coupling during development | ResearchBunny

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Abstract

This longitudinal neuroimaging study investigated the development of structure-function coupling in 84 typically developing children and 91 children with ADHD, aged 9-14. Typically developing children showed increased coupling strength in higher-order cognitive and sensory regions. Children with ADHD exhibited weaker overall coupling, particularly in prefrontal, superior temporal, and inferior parietal cortices, but increased coupling in other regions like the inferior frontal gyrus and superior parietal cortex. These findings suggest atypical coordinated white matter and functional connectivity development in ADHD.

Publisher

Translational Psychiatry

Published On

Authors

Shania Mereen Soman, Nandita Vijayakumar, Phoebe Thomson, Gareth Ball, Christian Hyde, Timothy J. Silk

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