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Copy number variation of the restorer *Rf4* underlies human selection of three-line hybrid rice breeding

Agriculture

Copy number variation of the restorer *Rf4* underlies human selection of three-line hybrid rice breeding

Z. Zhao, Z. Ding, et al.

This research reveals the early emergence of the Rf4 locus, a vital fertility restorer for rice breeding, ahead of the CMS-WA gene in wild rice. With 69 haplotypes generated in the Oryza genus and significant findings on the selection of Rf4 in modern cultivars, this study enhances our understanding of the CMS/Rf systems, opening new avenues for crop breeding. Conducted by Zhe Zhao, Zhi Ding, Jingjing Huang, Hengjun Meng, Zixu Zhang, Xin Gou, Huiwu Tang, Xianrong Xie, Jingyao Ping, Fangming Xiao, Yao-Guang Liu, Yongyao Xie, and Letian Chen.

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